Blastocarb

Country of origin: Mexico
Pharm-Group: Alkylating agents, platinum derivatives

Manufacturers: Lemery (Mexico)
International name: Carboplatin
Synonyms: Carboplatin, Carboplatin-Lance, Carboplatin-Teva, Carboplatin-Ebeve, Kemocarb, Paraplatin, Cycloplatin
Dosage forms: lyophilized powder for the preparation of an injection solution 50 mg, lyophilized powder for the preparation of an injection solution 150 mg, lyophilized powder for the preparation of an injection solution 450 mg
Composition: Active substance: Carboplatin.

Indications for use: Ovarian cancer, malignant testicular tumors, small cell lung cancer, squamous cell cancer of the head and neck, cancer of the cervix and uterine body, breast, soft tissue sarcoma.

Contraindications: Hypersensitivity (including to other drugs containing platinum), severe renal impairment, myelosuppression, pregnancy, lactation, clinical signs of bleeding.

Side effects: Myelosuppression: thrombocytopenia, leukopenia, anemia, increased susceptibility to infectious diseases, bleeding; Gastrointestinal disorders: nausea, vomiting, diarrhea, change in taste; decreased hearing acuity, paresthesia, impaired liver function, alopecia, increased creatinine and urea levels, hypomagnesemia, hypokalemia, hypocalcemia, fever, chills, allergic reactions.

Interaction: Pharmaceutically incompatible with aluminum salts. Strengthens (mutually) the nephrotoxicity of propranolol, aminoglycosides, diazoxide.

Overdose: No information.

Special instructions: It is necessary to conduct weekly monitoring of the cellular composition of the blood and laboratory parameters characterizing the function of the liver and kidneys.

Literature: Encyclopedia of Medicines, 2003.