Blood-retinal Barrier

The blood-retinal barrier is a physical and functional barrier that separates the blood vessels of the retina from the internal environment of the eye. It consists of several layers of cells and fibers that provide protection against harmful substances and microorganisms.

The blood-retinal barrier is an important element in the functioning of the eye, as it protects the retina from damage and infection. If the blood-retinal barrier is damaged or compromised, it can lead to serious eye conditions such as retinal detachment or glaucoma.

Main functions of the blood-retinal barrier:

  1. Protection against infections and other harmful substances. Cells of the blood-retinal barrier secrete substances that protect the retina from harmful influences.
  2. Regulation of metabolism in the retina. Barrier cells regulate metabolism in the retina, ensuring its normal functioning.
  3. Providing nutrition to the retina. Blood-retinal barrier cells provide nutrition to the retina by transporting nutrients across the barrier.
  4. Regulation of pressure inside the eye. Cells of the hemoretinal barrier are also involved in regulating pressure inside the eye, preventing its increase.
  5. Participation in the formation of visual perception. The blood-retinal barrier plays an important role in the formation of visual perception, ensuring the transmission of information from the retina to the brain.

Overall, the blood-retinal barrier performs many functions necessary for normal eye function. Disruption of its functions can lead to serious consequences for eye health.



*Blood-retinal barriers* are intercellular membranes that separate blood capillaries and the inner chamber of the eye. They play a key role in protecting the eyes from infections, toxins and other harmful substances coming from the blood. Moreover, the hematoretinal coating provides nutrients and oxygen to the retinal tissue and also removes carbon dioxide from the eye. Violation of the integrity of the blood-retinal barrier can lead to a number of diseases, such as glaucoma and diabetic retinopathy. In this article, we will look at the mechanisms that regulate the integrity of the blood-retinal barriers, the ways in which they are damaged, and the consequences that arise as a result of disruption of the blood-retinal function. We will also look at methods for correcting and preventing disorders associated with blood-retinal barriers.

Mechanisms of regulation by the blood-retinal barrier

Capillaries are the most important components of the hematoretinal lining, as they ensure the exchange of substances between the blood and the inner chamber of the eye. Maintaining capillary integrity requires the regulation of many factors, including the interaction between endothelial cells located on the inner surface of the capillary walls and autoantibodies produced by the immune system. Normally, autoantibodies and the cellular matrix on the inside of the capillary walls form a complex mixture that protects the capillaries from injury and damage.

Violation of the integrity of the blood-retinal barrier occurs under the influence of various factors, such as eye infections, ocular trauma, systemic diseases and changes in the composition of the cornea and lens. One of the key regulators of hemorrhagic integrity