Myeloma disease (myelomatosis) is a malignant disease of hematopoietic and lymphoid tissue. It is characterized by tumor growth of bone marrow plasma cells and their production of monoclonal immunoglobulins, which leads to impaired hematopoiesis and bone damage.
Multiple myeloma is also called myeloma, myelomatosis, plasmacytoma, reticuloplasmocytosis, Rustitsky's disease.
The main symptoms of multiple myeloma:
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Bone pain associated with osteoporosis and pathological fractures due to bone lesions.
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Anemia due to suppression of normal hematopoiesis in the bone marrow.
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Increased blood viscosity and coagulation disorders due to the high content of paraproteins.
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Kidney damage, manifested by proteinuria and renal failure.
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Recurrent infections due to immunodeficiency.
Diagnosis of myeloma is based on blood and urine tests, bone x-rays, and bone marrow biopsy. Treatment includes chemotherapy, stem cell transplantation, and radiation therapy. The prognosis for patients with myeloma is generally unfavorable.
Myeloma disease, or myelmo-Boas disease, is a blood disease characterized by malignant degeneration of hematopoietic tissue with the formation of tumors from immature plasma cells and the accumulation of methylated IgM in the blood. It was first described by the Russian scientist Alexander Alexandrovich Palchin. Myeloma tumors are characterized by proliferation