Serum sickness

Serum sickness: causes, symptoms and treatment

Serum sickness, also known as allergic serum sickness, is a rare but potentially serious complication that can occur after introducing large amounts of protein into the body. It mainly occurs in people who receive immunoglobulins or blood serum, but can also develop after receiving other drugs or vaccines.

The cause of Serum Disease is that the body begins to produce antibodies against the injected protein. This leads to an allergic reaction, which can manifest as skin rashes, fever, joint pain, swollen lymph nodes and other symptoms.

One of the most serious complications of Serum Illness is anaphylactic shock, which can occur within minutes to hours after protein administration. This condition requires immediate medical attention as it can lead to death.

Diagnosis of Serum disease is based on symptoms and a blood test for the presence of antibodies to the injected protein. Treatment may include antihistamines, corticosteroids, proton pump inhibitors, and other medications that help reduce the symptoms of an allergic reaction.

Overall, Serum sickness is a rare complication, but can be very serious, especially if not treated promptly. If you are at risk for developing this disease, be sure to discuss it with your doctor to make sure you receive the necessary precautions and treatment to avoid possible complications.



Serum sickness A number of diseases are described, the symptom of which is a serum or anaphylactic reaction when administered with anti-measles serum or other serum drugs. However, the essence of this condition has not been fully clarified. The assumption that the clinical manifestations of serum sickness are similar to serum vasculitis and granulomatosis cannot be ruled out. This disease has been described in children and adults and manifests itself in the form of serum fever with general malaise, headache, allergic exanthema, arthralgia, urticaria, peripheral lymphadenopathy and nodes. The criterion for diagnosis is the increase in specific antibodies in the paired serum. The absence of specific changes in the paired serum allows us to consider this variant of the serum disease as an independent disease. From serum b-