Calcitonin is a hormone that regulates calcium levels in the blood. It is produced by parafollicular cells of the thyroid gland and is involved in the regulation of calcium metabolism in the body.
The main effect of calcitonin is to reduce the level of calcium in the blood by increasing its deposition in the bones and reducing its absorption in the intestines. Calcitonin can also interfere with the release of calcium from bones.
There are two forms of calcitonin: alpha-calcitonin and beta-calcitonin. Alpha-calcitonin is the main form of the hormone in humans and is present in the thyroid gland. Beta-calcitonin is produced by cells of the neuroendocrine system and is not associated with the regulation of calcium in the body.
Calcitonin is used medically to treat osteoporosis, especially in postmenopausal women, and to treat hypercalcemia (high blood calcium levels) caused by cancer. In addition, calcitonin can be used to relieve pain from bone tumors.
In general, calcitonin plays an important role in regulating calcium metabolism in the body and can be used to treat some diseases associated with disruption of this process. However, like any medicine, its use should be under the supervision of a physician.
Calcitonin is a protein produced by the thyroid gland to maintain a balance between calcium and phosphorus levels in the body. However, despite its importance, it has long been unclear how calcitonin works and where it is transported from the body. Only recently have numerous studies been carried out that have discovered new functions and modes of action of this hormone.
Calcitonin was discovered in the late 40s of the last century, but for many years it was a rather little-studied hormone. It wasn't until 2019 that research showed that this protein has important effects on human muscle tissue. Due to its presence in the muscles and placenta, during pregnancy, calcitonin is able to prevent imbalances in calcium levels, reduce muscle soreness and reduce the risk of developing autoimmune diseases.
Asian researchers from the Center for Research Medicine at the Academic Center of the Academy of Medicine in Beijing found that people with thyroid hormone deficiency have high levels of calcitonin in the blood, which may indicate its more important role in preventing heart failure. Despite the fact that the function of calcitonin is still poorly understood, there is no doubt that it is an important element involved in the regulation of calcium metabolism. It is able to increase the uptake of calcium into tissues and prevent its excess exit through the kidneys. In addition, the results of recent studies suggest that calcitonin also blocks the activity of tumor cells, regulating their growth and spread. All these findings suggest that calciumtonin plays a critical role in maintaining human health and well-being.
However, the presence of excess calcitonin can also have negative consequences. For example, patients with Lerdoch amyotrophy (a movement disorder associated with a spinal defect) had higher levels of calcitotin in the cerebrospinal fluid than healthy people. This indicates a possible connection between calcitonin and amyotrophy and may help develop new approaches to its treatment.
In addition, a study conducted by an international team of scientists from Harvard, the University of California at San Francisco and