Coagulants

Coagulants (coagulantia; from Latin coagulans, coagulantis - causing clotting) are medications that promote blood clotting. They are used to stop bleeding, as well as for bleeding disorders.

The main groups of coagulants include:

1. Local hemostatic agents are substances that, when applied topically, stop bleeding (for example, collagen, gelatin, cellulose).

2. Antihemophilic drugs are blood products containing clotting factors (for example, cryoprecipitate, prothrombin complex).

3. Vitamin K is involved in the synthesis of coagulation factors by the liver.

4. Fibrinolysis inhibitors are substances that suppress the activity of enzymes that destroy fibrin clots (for example, aminocaproic acid).

Coagulants are widely used in medical practice in the treatment of various hemorrhagic conditions, including hemophilia, von Willebrand disease, thrombocytopenia and other disorders of the blood coagulation system. Correct and justified prescription of these drugs can effectively stop pathological bleeding.

In medicine and pharmaceuticals, coagulants are a group of substances that stimulate the coagulation process. Coagulation in a biological environment determines the reaction during which proteins coagulate. In the human body, blood is not just blood and only by itself does it not perform its function. It delivers biological substances right up to organs and tissues, and also protects the body from external penetration of poisons and various toxins. One of these important components of blood is fibrin. However, if the fibrin structure is disrupted, then a serious breakdown of the blood system occurs and human health is jeopardized. Thanks to the use of coagulators, the blood becomes viscous, gradually forming blood clots and coalescing in nodes. According to their pharmacological effect, they can be in different forms - solution, suppositories, cream or even tablets