Cryptococcosis

Cryptococcus is one of the most common and most dangerous infections associated with fungi of the genus Aspergillus, which can cause dangerous diseases in humans and animals.

Epidemiology and Pathogenesis Mycoses caused by Aspergillus spp. are usually associated with human exposure to an animal source. If we exclude HIV infection and AIDS, as well as cancer or granulomatosis, this issue is no longer relevant. In developed countries, along with fungi of the Eurotiales order, Aspergillus flavus and Aspergillus parasiticus, which cause cryptocroccosis, are also present. Aspergillus fumigatus is distributed primarily in hot and humid climates in Asia, South America, parts of Africa and Australia, indoors, on farms, and in agricultural products. Among animals, the causative agents of the disease are dogs, cats, and cattle. Aspergillus niger is best known in food products, candidiasis of the mucous membranes, gastrointestinal manifestations of allergies, inflammation of the respiratory system, skin, and wounds. Aspogillus also has other habitats, including eels, the waste products of bats. Fungi infect the soil in greenhouses, plant nurseries and sewers. Such symptoms have increased concentrations of IgE. Antigenic crosstalk persists between fungi of this family and the mold Aspergilloides furcatus, and the genus can cause local



Cryptococcosis is a disease associated with the presence in the body of a fungus of the genus **Cryptococcus**, which in 80% of cases is the causative agent of cryptococcosis. The hyphal stage of the fungus is pathogenic for the body. Unlike the causative agents of disseminated fungiosis, cryptococci do not produce pigment. They attack the nervous system, forming cryptococcal granulomas in the brain and other organs. Cryptococcus can be caused not only by Cryptococcus neoformans, but also by other fungi from the families Tuberculosaceae and Pucciniaceae. Fungi of the genus Coccidioides are the most common fungal infections affecting the central nervous system.[1] Recent studies show that cryptococcus is also capable of causing pneumonia and meningitis. However, cryptosporidium is represented by microscopic ciliates that primarily invade the vascular endothelium.[2]