Cytopathogenic dose

A cytopathogenic dose (from the Greek cytus - cell and pathos - suffering, disease + Greek -genes - generating) is a dose of ionizing radiation that causes cell death or disruption of their normal functioning.

The cytopathogenic effect of radiation manifests itself in damage to cellular structures, primarily chromosomes. This leads to cell death, disruption of division and differentiation processes.

The magnitude of the cytopathogenic dose depends on the type of cells being irradiated. The most radiosensitive cells are the cells of hematopoietic and lymphoid tissue, and germ cells. A dose of 1 Gy causes the death of up to 60% of human lymphocytes.

Thus, a cytopathogenic dose is a dose of ionizing radiation that leads to damage and death of body cells. Its value depends on the type of cells being irradiated.

A cytopathogenic dose is a dose of ionizing radiation that causes cell death or disruption of their functions.

The term "cytopathogenic" comes from the Greek words "cytus" - cell and "pathos" - suffering, disease. The ending "-genes" means "generating".

Ionizing radiation in doses exceeding cytopathogenic doses leads to the destruction of cellular structures and cell death. This is due to damage to DNA molecules and proteins under the influence of ionizing particles.

The magnitude of the cytopathogenic dose depends on the cell type. Cells that are actively dividing and differentiating are most sensitive to radiation. The cytopathogenic effect appears some time after irradiation, which is associated with disruption of cell division processes.

Exceeding the cytopathogenic dose leads to the development of radiation sickness and other adverse effects of radiation. Therefore, knowledge of cytopathogenic doses is important for radiation safety.