Depakine is an antiepileptic drug derived from valproic acid.
Producing countries: Hungary, France, Belgium, India.
Pharmaceutical group: anticonvulsants - valproates.
Manufacturers: Gedeon Richter, Sanofi-Aventis, Torrent Pharmaceuticals.
International name: valproic acid.
Synonyms: Apilepsin, Acediprol, Valparin HR, Depakin 300 enteric, Depakin Chrono, Depakin Chrono 500, Depakin-Chrono, Dipromal, Konvulex, Convulsofin, Orfiril, Everiden, Encorat.
Dosage forms: syrup 5.7%, powder for the preparation of an injection solution, tablets, enteric tablets, powder for the preparation of an intravenous solution.
Indications for use: various forms of epilepsy, childhood tics.
Contraindications: hypersensitivity, liver and pancreas diseases, bleeding, pregnancy, breastfeeding.
Side effects: nausea, vomiting, diarrhea, hepatotoxicity, drowsiness, tremor, leukopenia, thrombocytopenia, alopecia.
Interaction: enhances the effect of other anticonvulsants and sedatives. Increases the risk of liver damage and bleeding when used together with other drugs.