Diphenhydramine.

Diphenhydramine

Diphenhydramine is a drug that has a neurotoxic (parasympathetic, central anticholinergic), psychotropic (narcotic) effect.

In case of diphenhydramine poisoning, the following symptoms are observed: dry mouth, dizziness, nausea, muscle twitching, tachycardia, visual disturbances. The pupils are dilated, horizontal nystagmus is possible, the skin is dry and pale.

Psychomotor agitation, convulsions followed by loss of consciousness are also possible. A coma, a drop in blood pressure, and respiratory depression develop. When taken orally, numbness of the oral mucosa may occur.

Treatment for diphenhydramine poisoning includes:

1. When taken orally - gastric lavage through a tube lubricated with petroleum jelly, forced diuresis.

2. Administration of physostigmine - 1-2 ml of 0.05% solution subcutaneously repeatedly (for hallucinations, agitation, coma).

3. For agitation - aminazine or tizercin (2 ml of a 2.5% solution intramuscularly), for convulsions - diazepam (2 ml of a 0.5% solution intravenously).