Diphenhydramine

Diphenhydramine is an antiallergic, local anesthetic and antispasmodic drug. It also has a sedative and antiemetic effect.

Indications for use:

1. Allergic diseases (urticaria, angioedema, serum sickness)
2. Parkinson's disease
3. Sea and air sickness
4. As a sedative and hypnotic

Dosage:

1. Adults are prescribed 0.025-0.05 g orally 1-3 times a day
2. Children under 1 year - 0.002-0.005 g
3. From 2 to 5 years - 0.005-0.015 g
4. From 6 to 12 years - 0.015-0.03 g per dose

Maximum daily doses:

1. For adults: single dose 0.1 g, daily dose 0.25 g

Side effects:

1. Dizziness, headache
2. Dry mouth
3. Nausea
4. Drowsiness
5. General weakness

Release form:

1. Tablets 0.02; 0.03 and 0.05 g

Diphenhydramine: use, side effects and contraindications

Diphenhydramine, also known as diphenhydramine, is a histamine H1 receptor blocker used medically to treat allergic reactions and other conditions. The drug is produced by several companies in Russia, including AI CN Leksredstva, Akrikhin HFC, Allergen Stavropol, Aspharma and others.

The dosage form of Diphenhydramine includes an injection solution, tablets of various dosages, substance, sticks, suppositories and other forms. The active ingredient is diphenhydramine. The drug is used for the treatment of urticaria, hay fever, vasomotor rhinitis, pruritic dermatoses, allergic conjunctivitis, angioedema, complex therapy of anaphylactic shock, radiation sickness, bronchial asthma, gastric ulcer and hyperacid gastritis, parkinsonism, chorea, sea and air sickness, vomiting, syndrome Meniere and local anesthesia in patients with a history of allergic reactions to local anesthetic drugs.

However, Diphenhydramine has contraindications and restrictions for use. The drug is not recommended for people with hypersensitivity, breastfeeding, newborns and prematurity. There are also restrictions for use in cases of angle-closure glaucoma, prostatic hypertrophy, stenosing gastric and duodenal ulcers, pyloroduodenal obstruction, bladder neck stenosis and pregnancy.

In addition to contraindications, Diphenhydramine may cause side effects. From the nervous system and sensory organs, general weakness, fatigue, sedation, decreased attention, dizziness, drowsiness, headache, impaired coordination of movements, anxiety, increased excitability (especially in children), irritability, nervousness, insomnia, euphoria, confusion may be observed. consciousness, tremor, neuritis, convulsions and paresthesia. From the cardiovascular system and blood, hypotension, palpitations, tachycardia, extrasystole, agranulocytosis, thrombocytopenia and hemolytic anemia may occur. From the gastrointestinal tract, nausea, vomiting, constipation, diarrhea, dry mouth, epigastric pain and dyspepsia may be observed.

If side effects occur, you should consult your doctor, who may decide to reduce the dosage or discontinue the drug.

It should also be borne in mind that Diphenhydramine may enhance the effects of alcohol and other centrally acting drugs, so it is not recommended to take them together.

In general, Diphenhydramine is an effective drug for treating allergic reactions and other conditions, but its use should be discussed with your doctor and should not exceed the recommended dosage.