Disepton

Disepton: an effective combined antimicrobial agent

Diseptone, also known by the international name co-trimoxazole, is a combination antimicrobial agent produced by the pharmaceutical company Farmarus in Russia. It consists of two active components - sulfamethoxazole and trimethoprim, which interact and exhibit a synergistic effect, enhancing each other's effect.

Disepton is widely used in the treatment of infections of various etiologies caused by both gram-positive and gram-negative microorganisms. It is effective against respiratory tract infections, urinary tract infections, urogenital infections, skin and soft tissue infections, ENT infections, surgical infections, septicemia, meningitis, osteomyelitis, brain abscess, toxoplasmosis and whooping cough.

Diseptone is presented in the form of tablets containing 480 mg of active ingredients. The dosage and duration of treatment depend on the severity of the disease and the age of the patient.

Despite its high effectiveness, Disepton has a number of contraindications that must be taken into account when using it. These are hypersensitivity to sulfonamides or trimethoprim, liver or kidney failure, B12-deficiency anemia, agranulocytosis, leukopenia, glucose-6-phosphate dehydrogenase deficiency, pregnancy, breastfeeding and childhood.

In addition, Disepton can cause side effects such as dyspepsia, nausea, vomiting, anorexia, cholestatic and necrotizing hepatitis, increased transaminases and bilirubin, pseudomembranous enterocolitis, pancreatitis, stomatitis, glossitis, agranulocytosis, aplastic anemia, thrombocytopenia, hemolytic anemia, megaloblastic anemia , hypoprothrombinemia, methemoglobinemia, eosinophilia, crystalluria, renal failure, interstitial nephritis, increased plasma creatinine, toxic nephropathy with oliguria and anuria, allergic reactions and others.

In conclusion, Disepton is an effective combination antimicrobial drug that is widely used in the treatment of various infections. However, before using it, it is necessary to take into account contraindications and possible side effects. To properly prescribe Disepton and monitor its use, you should consult a doctor.