Doxycycline hyclate: everything you need to know
Doxycycline hyclate is a tetracycline antibiotic that is used to treat various infections caused by various bacteria. The drug is widely used in medicine due to its effectiveness and relative safety.
Production and dosage forms
Doxycycline hyclate is manufactured by Rugby in the United States. The drug is available in the following dosage forms: 50 mg capsules, 100 mg capsules and 100 mg tablets.
Active substance and international name
The active substance of doxycycline hyclate is doxycycline. The international name of the drug is doxycycline. The drug is also known under various synonyms, such as Apo-Doxy, Bassado, Vibramycin, Doxal, Doxibene and others.
Indications for use
Doxycycline hyclate is used to treat various infections caused by various bacteria. The drug is the drug of choice for the treatment of infections caused by rickettsia and borrelia. Doxycycline hyclate is also effective in treating infections caused by chlamydia, mycoplasma and other intracellular pathogens.
The drug is also effective in the treatment of respiratory tract infections, urinary tract infections, skin and soft tissue infections, and in the prevention of surgical infections.
Contraindications and side effects
Doxycycline hyclate is contraindicated in cases of hypersensitivity to doxycycline, porphyria, severe liver failure, leukopenia, pregnancy (in the second half), breastfeeding (breastfeeding should be avoided during treatment) and for children under 9 years of age.
Like any medicine, doxycycline hyclate can cause side effects. These may include dizziness, sweating, vascular collapse, nausea, vomiting, anorexia, abdominal pain, diarrhea, constipation, dysphagia, glossitis, esophagitis, dysbiosis, fungal infections, photosensitivity, allergic reactions and others.
Interaction with other drugs
When taking doxycycline hyclate simultaneously with preparations of iron, sodium bicarbonate, aluminum, calcium and magnesium salts, its effectiveness may decrease. In addition, doxycycline hyclate may enhance the effect of anticoagulants, which can lead to bleeding. When doxycycline hyclate is used concomitantly with other antibiotics, such as penicillins or cephalosporins, drug interactions may occur.
Reception and dosage
Doxycycline hyclate is taken orally regardless of food intake. The dosage of the drug depends on the type of infection, its severity and the general condition of the patient. Usually the drug is prescribed at a dose of 100 mg 2 times a day for 7-14 days