Electrophoretic Skin Test

An electrophoretic skin test is a method for studying vascular response based on the use of electrophoresis of certain physiologically active compounds, such as adrenaline, acetylcholine or histamine, followed by analysis of changes in the skin. This method allows you to assess the body's sensitivity to drugs and identify possible allergic reactions to taking them.

Electrophoresis is a process in which an electric current is used to move the molecules of a substance through a solution or gel. In the case of an electrophoretic skin test, molecules of a physiologically active compound are introduced into the skin through a microneedle, then moved towards the surface of the skin under the influence of an electric field. When the molecules reach the surface of the skin, they cause changes in skin color and texture, which allows us to determine whether there is a reaction to the injected compound.

The electrophoretic skin test method is widely used in medicine to diagnose allergic reactions to various drugs and to assess the sensitivity of patients to various allergens. It can also be useful in pharmacology to study interactions between drugs and the human body.

However, like any other research method, electrophoretic skin testing has its limitations and requires strict adherence to safety rules. Therefore, before conducting such a study, it is necessary to consult a doctor and make sure that it is safe for the patient.

Electrophoretic examination of the skin is a fairly common diagnostic, since it allows one to study the sensitivity of the body's skin to certain drugs.

Using this method, you can assess the state of the reflex and sympathetic parts of the autonomic nervous system, as well as the sensitive parts of the cerebral cortex, which are responsible for the work of the sweat glands, muscles and papillae of the skin. Thus, the electrophoretic method allows you to determine nociceptive lability when applying superficial skin irritations In addition, tests show the presence of a threshold, which determines the conduction of pain impulses from the periphery