Eosinophilic Index

Eosinophilic index

The eosinophilic index is an indicator of the maturation of acidophilic granulocytes (eosinophils) in the bone marrow, representing the ratio of the number of young cells to the number of mature ones.

Eosinophils are special white blood cells that play an important role in the body's immune defense. They are produced in the bone marrow from stem cells and undergo several stages of maturation.

Young eosinophils are called promyelocytes and myelocytes. They are not yet fully formed and are not able to perform their protective functions. Mature cells have a characteristic granularity in the cytoplasm and can migrate into tissues to fight pathogens.

The eosinophilic index reflects the ratio of immature and mature forms. Its normal values ​​are 1-3%. An increase in the index indicates a violation of eosinophil maturation, which can be observed with various diseases and the use of certain medications.

Thus, the eosinophilic index provides important information about the state of bone marrow hematopoiesis and can be used for diagnosis and monitoring of various pathological processes.

Eosinophil Index! **Synonyms** *Eositropoiesis-stimulating factor*

EI, EBFI

**Description** Eosinophil indices and aging parameters EI is a numerical value that is calculated by measuring the number of young or old forms of eosinophils and pronormocytes/promyelocytes found in the circulating blood and bone marrow. This parameter helps determine the characteristics of eosinopenia stimulation in human blood. An absolute EI of less than 3 is diagnostically insufficient to reliably determine increased IL-5 production. Significant absolute UI in