Erythema Persistent Erythromelalgic

Erythema Persistent Erythromelalgic: Rare dermatological syndrome

Erythema persistent erythromelalgic (erythema EPE) is a rare dermatological disorder characterized by a combination of chronic erythema (redness of the skin) and erythromelalgia (painful redness and burning of the extremities). This condition often results in significant discomfort and disruption to patients' quality of life, and requires a specialized approach to diagnosis and treatment.

Symptoms of PEE erythema can range from mild to severe and may occur in one or both lower extremities. Typically, patients describe a sensation of tingling, burning and intense pain, which intensifies when the ambient temperature rises or during physical activity. Often the symptoms become more painful while sitting or standing, and patients experience relief by putting their legs in cold water or raising them up.

The reasons for the development of PEE erythema are not yet fully understood. However, there are suggestions about the possible role of a disorder of the peripheral nervous system, a disorder of blood microcirculation, or dysfunction of the vascular endothelium. It is possible that these factors interact with each other, leading to the development of the syndrome.

The diagnosis of erythema PEE is usually based on characteristic clinical signs, previous events or factors that cause or worsen symptoms, and the exclusion of other possible causes of pain and erythema. Laboratory tests, including blood tests and tests of nervous system function, may be needed to confirm the diagnosis.

Treatment of erythema PEE is aimed at relieving symptoms and improving the patient's quality of life. This may include the prescription of anti-inflammatory and pain medications, vasodilators, antidepressants and antiepileptic drugs. In addition, patients are advised to avoid factors that may aggravate symptoms, such as elevated ambient temperatures, physical stress, and prolonged standing.

Although erythema PEE is a rare condition, it can significantly affect patients' quality of life by limiting their ability to perform normal daily tasks. The disease requires long-term care and monitoring by doctors.

In conclusion, erythema persistent erythromelalgic (erythema EPE) is a rare dermatological disorder that is characterized by chronic redness of the skin and painful redness and burning of the extremities. It can significantly affect patients' quality of life, causing discomfort and limitations in daily activities. The disease requires a specialized approach to diagnosis and treatment, and patients are recommended to be constantly monitored by doctors. Further research is needed to better understand the causes and mechanisms of development of this rare syndrome and to develop effective treatments.



Erythema persistent, or erythromelalgia, is a chronic inflammatory skin disease that manifests itself in the form of persistent redness of the skin, swelling and burning. The disease occurs in both adults and children, but is most often observed in women aged 40 to 60 years.

The reasons for the development of persistent erythema are not fully understood, but it is believed that the disease occurs due to dysfunction of nerve cells that transmit signals from the skin to the brain. This leads to an inadequate response of the body to irritants and disturbances in skin sensitivity.

Signs of persistent erythema can appear in several forms, for example, in the form of diffuse redness, limited in area, or even one patch of skin on the leg or arm. The skin may be dry, hot and tight, and may show signs of scratching and crusting.

Treatment for erythema permanent is the use of anti-inflammatory creams, ointments and topical medications that help reduce itching and swelling. In severe cases, intravenous drugs such as glucocorticoids can be used, which provide rapid relief but have many side effects.