Platelet-Derived Growth Factor (Pdgf)

Platelet-derived growth factor is one of the growth factors that plays an important role in the development and functioning of platelets. It was discovered in the 1970s and named platelet-derived growth factor (Pdgf).

Platelet-derived growth factor is a protein produced by platelets that is capable of stimulating the proliferation and migration of other cells, including vascular endothelial cells, fibroblasts, and smooth muscle cells.

In pathology, when the number of platelets decreases, the level of platelet growth factor in the blood also decreases, which can lead to dysfunction of the vascular wall and the development of thrombosis.

Platelet-derived growth factors can be used to treat thrombosis and other diseases associated with impaired platelet function. Experimental studies have shown that administration of Pdgf can stimulate the growth of new platelets and increase their number in the blood.

In addition, Pdgf can also be used to stimulate wound healing and tissue repair after injury and surgery.

Thus, platelet-derived growth factor plays an important role in the regulation of platelet function and can be used in the treatment of various diseases associated with thrombosis and vascular dysfunction.

Platelet-derived growth factor is one of the most important factors regulating the development and functioning of platelets. Platelets are involved in blood clotting through a process called thrombocytosis (formation of blood clots). The role of platelets in this system is to provide strengthening of blood vessels when endothelial cells are damaged or dividing and activate platelet-derived growth factors. It is these growth factors that promote the growth of new platelets from damaged or nascent cells.

Platelet-derived growth factor belongs to a family of growth factors that can be classified as basic or basophilic growth factors (PDGF). These growth factors serve as the main mediators of the cell cycle, and also take part in the processes of initiation and maintenance of fibrosis, and are regulated growth factors of angiogenesis. PDP also exerts neutrophil growth factor (PEGF)-mediated induction on vascular tissue.

The platelet-derived growth factor (PDGF) was discovered in the early 1980s as a result of research into the causes of thrombosis in the circulatory system. Genetic disease - defective blood clotting. The clotting time may exceed the norm by up to 30 times. The fact is that platelets simply do not break down into fragments (agglu