Phenindione (Phenindiope)

Phenindione is a medicinal substance belonging to the group of anticoagulants. Used to treat thrombosis of blood vessels of the heart and extremities.

The mechanism of action is based on inhibition of the enzyme vitamin K epoxide reductase, which leads to disruption of the synthesis of blood coagulation factors II, VII, IX and X in the liver.

Phenindione can be administered orally in the form of tablets or administered parenterally by injection.

Possible side effects when taking phenindione: allergic skin rashes, fever, diarrhea.

Phenindione is marketed under the trade name Dindevan.



Pheniidone is a medicinal substance that is used to prevent and treat thrombosis of blood vessels, especially the arteries of the heart. Unlike many other drugs, Phenidione has lower toxicity, which makes it safer.

Phenidion is taken both orally and by injection. After oral administration, the medicine is quickly absorbed by the mucous membrane of the stomach and intestines, and then enters the blood. The largest amount of Phenidion is concentrated in the tissues of the lung and liver. It binds to plasma proteins, while its interaction with other substances is minimal. The half-life of the drug is approximately



Phenindione: anticoagulant for the treatment of thrombosis

Phenindione, also known as Phenindione, is an effective drug from the group of anticoagulants. This drug is widely used to treat thrombosis that can occur in the blood vessels of the heart and limbs. Phenindione has the trade name Dindevan and is available in tablet or injection form.

The action of Phenindione is based on its ability to reduce blood clotting. It affects factors responsible for blood clotting, such as vitamin K-dependent clotting factors. This helps prevent blood clots and reduce the risk of developing thrombosis.

The use of Phenindione can be carried out either orally, taking tablets, or in the form of injections, which can be prescribed by a doctor depending on the specific situation and needs of the patient. The dosage and regimen should be determined by a medical specialist based on the individual characteristics of the patient.

Like any medicine, Phenindione may cause some side effects. Some of the common side effects associated with the use of Phenindione include skin rashes, fever, and diarrhea. If the patient experiences serious or prolonged side effects, the patient should consult a doctor.

Before starting treatment with Phenindione, you should discuss all existing medical problems and medications you are taking with your doctor. Some conditions and drugs may interact with Phenindione and may require dosage adjustments or alternative treatment options.

In conclusion, Phenindione is an effective drug used to treat thrombosis. Thanks to its anticoagulant effect, it helps prevent the formation of blood clots and reduce the risk of thrombosis. However, before starting treatment with Phenindione, you should consult your doctor to ensure its safety and effectiveness in your particular case.