Koebner Phenomenon, Isomorphic Response

Koebner Phenomenon, or Isomorphic Response, is a phenomenon observed in some skin diseases, especially psoriasis and lichen planus. It is characterized by long lines of skin lesions in response to injury such as a cut, burn, or scratching.

When the Koebner phenomenon occurs, new rashes appear on the skin at the sites of injury. These rashes are isomorphic (i.e. identical) to the main skin process. Thus, with psoriasis, typical psoriatic plaques appear in the area of ​​injury, and with lichen planus, characteristic papules appear.

Koebner's phenomenon was first described by German dermatologist Heinrich Koebner in 1872. He observed the appearance of psoriatic rashes on the skin of patients in areas of scratches and cuts.

This phenomenon has diagnostic significance, since it allows one to distinguish some chronic dermatoses from acute skin processes. In addition, it may indicate an exacerbation of the disease.

Koebner phenomenon is a phenomenon in which the skin reacts to damage in the form of lines or streaks. This phenomenon is observed in some skin diseases such as psoriasis and lichen planus. In this case, the skin reacts to injury in the form of a break in the skin, such as a cut, burn, or scratching, and forms lines or stripes on the skin.

One explanation for the Koebner phenomenon is the isomorphic response, which suggests that the skin reacts to different types of damage with the same lines or stripes, regardless of what type of damage was caused. This may be due to the fact that the skin has certain mechanisms that respond to different types of damage, and these mechanisms can lead to the formation of similar lines or stripes on the skin.

The Koebner phenomenon and the isomorphic reaction are important for understanding skin diseases and their treatment. Knowing how the skin reacts to injury can help doctors more accurately diagnose and treat skin conditions. In addition, understanding the mechanisms underlying the isomorphic response may lead to the development of new treatments for skin diseases.

Koebner phenomenon and isomorphic reaction.

The Koebner phenomenon is a clinical observation that appeared at the end of the 18th century. Its essence lies in the fact that a certain physiological or functional activity experienced or imagined by the patient provokes the formation of a similar defect in the tissues of a particular organ of the body, but under identical conditions, for example, repeated and other infections. An important point is that the changes that occur on the skin are often completely “reflected” in other organs and tissues.

However, in addition to the obvious skin response, the affected area also has functional (or even cerebral) similar in localization