Fibrinolysis (Fibrinolysis)

Fibrinolysis is the process of dissolving blood clots, including the breakdown of the insoluble protein fibrin by the enzyme plasmin. Plasmin is present in blood plasma in the form of an inactive precursor - plasminogen, which is activated simultaneously with the blood clotting process.

Typically, the human body maintains a balance between the processes of blood coagulation and fibrinolysis. However, an abnormal increase in fibrinolytic activity can lead to excessive dissolution of blood clots and extensive bleeding.

Thus, fibrinolysis plays an important role in maintaining homeostasis by preventing excessive thrombus formation while limiting excessive clot dissolution. Disturbance of this balance is the cause of many serious diseases.



Fibrinolysis is the process of dissolving blood clots that occurs in the circulatory system. It involves the breakdown of insoluble fibrin proteins by the enzyme plasmin, which is present in the blood in an inactive form - plasminogen. When the blood clots, plasminogen is activated and begins to break down fibrin. As a result of this process, blood clots dissolve, which facilitates their removal from the circulatory system.

However, if fibrinolysis accelerates, it can lead to extensive bleeding in a person. This can happen, for example, with certain blood disorders or when taking certain medications. Therefore, it is important to monitor the level of fibrinolysis in the blood and monitor its normal balance.

Fibrinolysis plays an important role in maintaining the health and functioning of the human circulatory system. It helps prevent the formation of blood clots, which can lead to serious illnesses such as heart attack, stroke, or pulmonary embolism. In addition, fibrinolysis is involved in the process of wound healing and tissue restoration after injury or surgery.

In general, fibrinolysis is an important process that is necessary for the normal functioning of the circulatory system and the maintenance of human health. However, its imbalance can lead to serious consequences, so it is important to monitor the level of fibrinolysis and take measures to control it if necessary.



Fibrinolysis is the process of dissolving a blood clot under the action of enzymes. This process is an important part of hemostasis, a process that regulates blood clotting and prevents blood loss.

Fibrinolysis begins when the concentration of plasmin in the blood increases, an enzyme that breaks down the protein fibrin, which forms a clot. Plasmin is formed as a result of the activation of plasminogen, a passive precursor found in plasma. Activation of plasminogen occurs simultaneously with the activation of other coagulation factors such as thrombin and factor XII.

Abnormal fibrinolysis can lead to extensive bleeding, especially if blood vessels are damaged. This can happen, for example, during surgery, injury or illness such as pulmonary embolism or DIC (disseminated intravascular coagulation).

Normally, the balance between coagulation and fibrinolysis is maintained in the body. However, under certain conditions, this balance can be disrupted, leading to the development of pathological conditions such as bleeding.