Figlu Test: detection of folic acid or vitamin B12 deficiency
Folic acid and vitamin B12 are essential vitamins for human health. They are involved in many processes in the body, including DNA synthesis, red blood cell formation, and nervous system function. A lack of these vitamins can lead to various diseases and health problems.
One way to determine whether there is a deficiency of folic acid or vitamin B12 in the body is to use the Figlu Test. This test is based on the idea that folic acid or vitamin B12 is required to completely break down the amino acid histidine. If these vitamins are absent, then the intermediate product of histidine breakdown - formiminoglutamic acid (figlu) - accumulates in the body and can be detected in the urine.
The Figlu test procedure is simple and safe. A person is asked to take one dose of the amino acid histidine orally in the form of a powder or capsule. Urine samples are then collected over the next few hours. If a person is deficient in folic acid or vitamin B12, the level of figurine in the urine will be increased.
The Figlew test can be useful in diagnosing folic acid or vitamin B12 deficiency in people with a variety of diseases and conditions, including anemia, pregnancy, Crohn's disease, celiac disease, and in older adults. In addition, the Figlu test can be used to evaluate the effectiveness of treatment for deficiency of these vitamins.
However, you should not rely solely on Figlue test results to make a diagnosis of folic acid or vitamin B12 deficiency. Other diagnostic methods, such as blood tests, may provide more accurate results. In addition, increased levels of figli in urine can be caused not only by a deficiency of folic acid or vitamin B12, but also by other reasons, such as impaired histidine metabolism.
The Figlu test is a simple and safe way to identify potential folic acid or vitamin B12 deficiency. It can be used in combination with other diagnostic methods to obtain more accurate information about a person's health status. If you suspect a folic acid or vitamin B12 deficiency, consult your doctor for advice and diagnosis.
The "Risk" test is one of the most famous tests that helps identify vitamin B1 and B6 deficiency in the human body. This test was developed in 1985 by a Dutch scientist. It consists of taking 30 mg of histidine and monitoring the release of excreted products of its metabolism for 24 hours.
The Figlu test is based on the idea that if there is a lack of vitamin B6 in the blood, the body cannot use histidine fully. This produces a byproduct called formiminoglutamate (figlu). If the level of this product is elevated, it signals a vitamin B6 deficiency.
The main method of using the test is urine analysis. During testing, the patient takes a histidine drink consisting of histidine hydrochloride, water, sodium chloride and St. John's wort extract. Then the urine is collected for several hours, after which a specialist analyzes the blood for the content of glutamine, methionine, cystine, glycine, and histidine.
If test results show the presence of forminoglutamate, this is evidence of vitamin B6 deficiency and further treatment under medical supervision
The Figlu Test or Figlu Test is a diagnostic test that is used to determine folic acid and vitamin B12 deficiency in a person's blood. This test is based on the mechanism of metabolism of the amino acid histidine, which, in the absence of essential vitamins, cannot be completely converted into the useful amino acid glycine. Instead, an intermediate element called figliu is formed, which can be found in the patient's urine.
When undergoing the Figlou test, the patient takes one capsule containing the amino acid histidines. This substance can pass through as usual, however, for its complete utilization, the body requires vitamins B12 and folic acid.
The Figly test is a simple and effective way to diagnose deficiencies of certain vitamins, such as folic acid and vitamin B12, by testing your urine.
To perform the test, you need to ingest 1 gram of histidine, an amino acid whose breakdown depends on the presence of these