Fotrin For Injection

"Photrin for injection: a detailed review of the drug" The drug Photrin (Fotretam) is a cytostatic agent containing a group of ethyleneimines and ethylenediamines, which is used as an anticancer agent. This drug has the international name Photretam and synonyms in various countries, including Fotherotin. Photrin belongs to the group of cytostatics used in medicine to treat cancer. The drug is used as an injection and has a pronounced suppression of cell growth.

Pharmacological action of Photrin Photrin inhibits cell mitosis by binding to DNA. As a result, the drug slows down the rate of cell division and has an antitumor effect. When Photrin-containing chemotherapy regimens are used, a decrease in the Karnofsky index, a reduction in tumor size, and an increase in hemoglobin levels are observed. In addition, Photrin also has anti-inflammatory and analgesic effects. Indications and contraindications Photrin is intended for use in oncology. It is used in combination with other chemotherapy drugs to fight certain types of cancer such as breast, lung, prostate, etc. The drug should be prescribed with caution in the presence of thrombocytopenia, leukopenia, severe anemia, when used with drugs that have a strong antiprotozoal effect, as well as in the presence of a deficiency of glucose in the blood.

Photorin for injection has low bioavailability and high binding to plasma proteins. The maximum concentration of Photrin is established 6 hours after administration. The half-life is 12 hours in normal renal function and 24 hours in renal disease. The drug is quickly eliminated from the body through the kidneys. About 80% of the administered dose is excreted in the urine as unchanged Photrin or its metabolite. The pharmacokinetics of Photrin may be altered by impaired renal or hepatic function.

Overall, Photrin is effective in the fight against cancer. However, like any other medicine, it has its contraindications and side effects that should be taken into account before using it. I recommend consulting with your doctor to obtain additional information and prescribe the optimal treatment regimen.