Friedlander's Disease

Friedlander's disease

Friedlander's disease is an autoimmune disease accompanied by severe damage to the pancreas, peripancreatic tissue and adjacent areas. The muscles of the tongue, larynx, trachea, duodenum, mesenteric and retroperitoneal lymph nodes are also affected. Often accompanied by a picture of pancreatitis. The main histological feature is lymphoplasmacytic infiltration of the pancreas with the formation of lymphoid accumulations around the islets of Langerhans. Previously, this disease was also referred to as bubonic spleen, although this term is not very accurate diagnostically. Friedman's disease usually affects men and can manifest in various forms of the disease, such as pancreatic fibrosis and chronic inflammation around the pancreas. Symptoms may include persistent nausea, vomiting, abdominal pain, diabetes and pancreatitis. Treatment may include drug therapy, surgery, or immunotherapy. However, many patients suffer from serious complications, including bacterial peritonitis and Sheehan's syndrome. Therefore, diagnosis and treatment of Friedmann's disease must be timely and effective to improve the patient's quality of life.