Country of origin: Poland, Goedecke/Parke-Davis Germany, Polfa Poland
Pharm-Group: Agents that stimulate alpha and beta adrenergic receptors
Manufacturers: Warsaw Pharmaceutical Plant Polfa (Poland), Goedecke/Parke-Davies (Germany), Polfa (Poland)
International name: Xylometazoline
Synonyms: Brizolin, Grippostad Rino, Dlynos, Doctor Theiss Nazolin, Xylene, Xylobene, Xylometazoline, Xymelin, Nasal aerosol, Nazenspray E-ratiopharm, Nazenspray K-ratiopharm, Olint, Otrivin, Rinonorm, Rinostop, Tizin xylo, Farmazolin
Dosage forms: nasal drops 0.05%, nasal drops 0.1%, non-dosed spray 0.1%, dosed spray 0.05%, nasal drops for children 0.05%, aerosol, nasal gel 0.05%
Composition: Active substance - xylometazoline.
Indications for use: Acute allergic rhinitis, hay fever, sinusitis, otitis media (to reduce swelling of the nasopharyngeal mucosa); preparing the patient for diagnostic procedures in the nasal passages.
Contraindications: Hypersensitivity, arterial hypertension, tachycardia, severe atherosclerosis, glaucoma, atrophic rhinitis, hyperthyroidism, pregnancy, breastfeeding.
Side effects: With frequent or prolonged use - irritation of the mucous membrane, burning, tingling, sneezing, dryness, hypersecretion. Rarely - swelling of the nasal mucosa, palpitations, heart rhythm disturbances, increased blood pressure, headache, vomiting, sleep disturbance, visual disturbances. With long-term use of high doses - depression.
Interaction: Incompatible with MAO inhibitors and tricyclic antidepressants.
Overdose: Symptoms: increased side effects. Treatment: symptomatic.
Special instructions: The aerosol is used in children under 3 years of age. Nasal drops with a concentration of the active substance of 1 mg/ml for children under 2 years of age are prescribed only by a doctor. Should not be used for a long time (for example, for chronic rhinitis). For colds, in cases where crusts form in the nose, it is preferable to administer it in the form of a gel.
Literature:
- Encyclopedia of Medicines 2004.