Ganglioplegic Drugs

Ganglioplegics are drugs that cause peripheral nerve palsy and are used in medicine to treat various diseases.

Ganglioplegia is a condition in which peripheral nerves are paralyzed and no longer transmit nerve impulses. This can be caused by a variety of reasons, including injury, infection, tumors, and medications. Ganglioplegia can lead to loss of sensation, muscle paralysis, and other serious complications.

One of the most well-known ganglioplegic drugs is atropine. It blocks the receptors responsible for transmitting nerve impulses in peripheral nerves, which leads to their paralysis. Atropine is used to treat glaucoma and also to prevent side effects from other medications.

Another ganglioplegic drug is scopolamine. It also blocks nerve receptors and is used to treat pain and muscle spasms. Scopolamine is often used in anesthesiology to reduce pain during surgery.

In addition, there are other ganglioplegic drugs such as platyphylline, hyoscine and benzohexonium. They are also used to treat various diseases associated with nerve disorders.

However, it should be noted that the use of ganglioplegics may have side effects such as dry mouth, constipation, decreased blood pressure, and abnormal heart rhythms. Therefore, before using these drugs, you should consult your doctor and strictly follow the instructions for dosage and duration of treatment.

Ganglioplexic or ganglionic drugs (from the Latin ganglion - ganglion) are one of the main groups of neurotoxic drugs and are used to treat various diseases of the nervous system. They work through disruption of the function of neuromuscular synapses, which leads to the cessation of the transmission of nerve impulses responsible for muscle contraction. Gangliopsis is used in a variety of clinical situations, including the treatment of miosis and skeletal muscle relaxation before surgery, as well as in neurological diseases such as myasthenia gravis, myotonia and other muscular dystrophies.

Gangliosnis-containing drugs can be in the form of tablets, capsules, injection solutions or ampoules for intravenous infusion, depending on their form and method of administration. Some, such as botulinum toxin, are used only in microdoses injected into a muscle, but others, such as anticholinesterase agents, can be taken orally or intravenously.

How do ganglioplexics work? Ganglios block the transmission of nerve impulses through muscle fibers. This happens in two ways. The initial mechanism is by irreversibly inhibiting feedback to motor neurons, inhibiting potassium channels, and preventing the release of the neurotransmitter that signals muscle contraction. This process is also known as motor nerve palsy and is especially effective on skeletal muscles.

The second mechanism of the work of gangliopsychics is associated with a decrease in impulse conduction through the nerve cell. This means that signals from the nerve to the muscle cell become less effective in suppressing the electrical activity of the cell membranes,