Gangrene Chemical

Chemical gangrene is tissue necrosis caused by local exposure to strong acids, caustic alkalis and some other chemicals.

Causes of chemical gangrene:

  1. Contact with skin or mucous membranes of concentrated acids (sulfuric, hydrochloric, nitric) or alkalis (caustic soda, caustic potassium). This leads to tissue necrosis at the site of contact.

  2. Exposure to certain chemicals used in industry and agriculture - phenol, carbolic acid, arsenic hydrogen, phosphorus, etc.

  3. Ingestion of certain toxic substances that cause necrosis of the mucous membrane of the digestive tract (acids, alkalis, phosphorus).

Pathological changes in chemical gangrene are characterized by the development of tissue necrosis in the area of ​​influence of the irritating agent, followed by the involvement of surrounding tissues in the inflammatory process.

Clinical manifestations: pain, hyperemia and swelling of tissues, formation of ulcers and necrotic scabs at the site of contact with the chemical. With deep lesions, symptoms of intoxication appear.

Treatment of chemical gangrene includes washing the affected area with antidote solutions, necrectomy, antibacterial therapy, and vitamin therapy. If not treated in a timely manner, amputation of the affected organ is possible.

The prognosis for chemical gangrene depends on the timing of the start of treatment, the area and depth of the lesion. Timely initiation of complex treatment in most cases leads to recovery.



Chemical gangrene is an acute disease that occurs as a result of chemical exposure to body tissue. It occurs when the skin is exposed to prolonged exposure to strong acids, alkalis or other chemical compounds that cause chemical burns to tissues. This can happen during chemical production, when working with hazardous chemicals, etc.

One of the most common cases of gangrene is working in paint and varnish production. When dyeing fabrics or wood, an acidic solution can cause a chemical burn to the skin, which leads to illness.