Blood-Ophthalmic Barrier

The blood-ophthalmic barrier is a physiological barrier that separates blood and intraocular fluid. It protects the eye from infections and other harmful substances that can enter the body through the blood.

The blood-ophthalmic barrier consists of several layers. The first layer is the capillary endothelium, which is located on the inner surface of the capillaries. The second layer is the basement membrane, which separates the endothelium from the intraocular fluid. The third layer is the epithelium, which covers the surface of the eye.

Functions of the blood-ophthalmic barrier:

  1. Protecting your eyes from infections and other harmful substances.
  2. Regulation of pressure inside the eye.
  3. Monitoring the level of fluid in the eye.
  4. Participation in the metabolism between blood and intraocular fluid.

Violation of the blood-ophthalmic barrier can lead to various eye diseases, such as glaucoma, retinal detachment, cataracts and others. Therefore, it is important to maintain eye health and monitor the condition of the blood-ophthalmic barrier.



The hematological ophthalmic barrier is a special system of interaction between the blood and the connective tissue of the eye; it is also called the “eye barrier”. It is located along the border between the epidermis and the lens itself, as well as the Rosenthal and Weigers membranes.

The barrier performs the following functions:

Forms a superficial protective shell for the eye and its structures. Blocks access to pathogenic microbial material in the blood to the capillary system. Supports the microenvironment of ocular tissues through immunological mechanisms. Affects the proliferative activity of cells and their