Blood Parenchymal Barrier

Hematoparenchymatous The barrier is a physiological barrier that separates the blood and the parenchyma (internal tissue) of an organ. It is composed of several layers of cells, including endothelial cells, pericytes, fibroblasts and macrophages.

Endothelial cells form the first layer of the blood parenchymal barrier and are key components of this barrier. They provide a barrier function, regulating the metabolism between blood and parenchyma. They are also involved in regulating blood clotting and the immune response.

Pericytes are connective tissue cells that surround capillaries and participate in the formation of the blood-parenchymal barrier. Pericytes provide mechanical support to endothelial cells and create an environment that promotes the exchange of substances between the blood and the parenchyma.

Fibroblasts also play an important role in the formation of the blood-parenchymal barrier. These cells synthesize collagen, which forms the basis of connective tissue and provides mechanical support to endothelial cells and pericytes. Fibroblasts are also involved in the process of wound healing and tissue regeneration.

Macrophages are phagocytic cells that participate in the immune response and defense of the body against infections. They also play a role in maintaining the blood-parenchymal barrier by removing damaged cells and metabolic waste from the parenchyma.

In general, the blood parenchymal barrier plays an important role in protecting the parenchyma from infections, toxins and other harmful factors. It ensures a balance between the metabolism between blood and tissues and maintains the normal function of the organs and systems of the body.

The hemato-parenchymal (hemato- + lat. parenchyma - “kidney”) barrier is an anatomical and physiological barrier between blood and tissues, which performs a number of important functions. It consists of blood vessels and parenchyma, which is the tissue found between the blood vessels.

The blood parenchymal barrier plays an important role in protecting the body from various pathogenic agents such as bacteria, viruses and toxins. It prevents these agents from penetrating tissues and organs and also protects them from damage.

The blood vessels that form the basis of the blood-parenchymal barrier are highly permeable to many substances, including hormones, nutrients and other biologically active substances. However, they are also the site for the formation of antibodies and other defense mechanisms.

Parenchyma, which is located between blood vessels, plays an important role in maintaining homeostasis and protecting the body from external influences. It contains many cells that are involved in metabolic processes, regulation of the immune system and other functions.

Thus, the blood parenchymal barrier is an important component of the body's immune system, which protects it from various pathogens. Violation of this barrier can lead to various diseases and complications, so it is necessary to maintain its normal function.