Gentamicin (Gentamicin)

Gentamicin is an antibiotic from the aminoglycoside group. It is used to treat infections caused by various bacteria. Gentamicin may be given by injection, applied to the skin as a cream, or used as eye or ear drops. When used in high doses, damage to the kidneys and hearing is sometimes observed.

Gentamicin is marketed under the trade names Cidomycin, Garamycin and Genticin. This antibiotic is widely used to treat serious bacterial infections.



Gentamicin is an aminoglycoside antibiotic widely used to treat infections caused by various bacteria. It has a strong bactericidal effect and a wide spectrum of activity, which makes it effective in combating various types of bacterial infections.

Gentamicin can be prescribed in a variety of forms, including injections, topical cream, and eye or ear drops. This allows it to be used depending on the specific type of infection and its location.

The drug is highly effective against many gram-negative bacteria, such as Escherichia coli, Klebsiella pneumoniae and Pseudomonas aeruginosa. It may also be effective against some gram-positive bacteria, including Staphylococcus aureus and Streptococcus species.

However, it should be noted that gentamicin may cause certain side effects when taken. In high doses, it can negatively affect kidney function and hearing. Therefore, it is important to strictly follow your doctor’s recommendations and take antibiotics only as directed.

Gentamicin is available under various trade names, including Cidomycin, Garamycin, and Genticin. These drugs may come in different forms and dosages, but they all contain gentamicin as an active ingredient.

Before using gentamicin, you should consult your doctor to determine the correct dosage and method of administration. You should also tell your doctor about any existing allergic reactions or other health problems to avoid possible complications.

Overall, gentamicin is an effective antibiotic that is widely used to treat a variety of bacterial infections. However, its use should be under the supervision of a physician to minimize the risks of side effects and ensure maximum effectiveness of the treatment.



Gentamycin *(Gentamycin)*: a broad-spectrum antibiotic from the aminoglycoside group.

Gentamicin is an antibiotic belonging to the group of aminoglycoside antibiotics that are widely used to treat various infections. It was developed in the 1960s from the molecule gentamicin C, derived from Streptomyces griseus, a strain of bacteria that naturally produces gentamicin acid. Since then, several clones and subclones of the genotom of this organism have been produced, leading to various forms and modifications of the antibiotic molecule.

The main mechanism of action of gentamicin is binding to the 30S ribosomal subunit and inhibition of protein synthesis caused by gram-negative microorganisms and tuberculocides, which are aerobic bacteria that cause various infectious diseases. Gentamicin is effective against many microorganisms, including the bacteria Pseudomonas, Proteus, Klebsiella, Serratia, as well as Mycobacterium tuberculosis, Neisseria gonorrhoeae and Neisseria meningitidis. Resistance to gentamicin develops slowly in Gram-negative and anaerobic bacteria such as Bacteroides fragilis, but rapidly in Mycobacterium lophitenaceus and Protea. Some tuberculocides, such as Mycobacterium smegmatis, can grow in the presence of gentamicin. Commercially available forms of gentamicin include injection solution, topical cream, and eye drops. It is usually administered intramuscularly, but may also be in the form of an internal gel, an ocular decongestant, or an intravenous solution. Side effects from gentamicin use typically include systemic distress, renal dysfunction, peripheral nerve damage, or transverse irritation. In some cases, especially when using high doses, complications due to infection or kidney disease may occur. Hearing dysfunction or paralysis may also occur. The use of gentamicin is based on empirical data, and its use should be carefully justified and well suited for the intended purpose, and the patient's symptoms should be monitored throughout the course of treatment, since repeated administration of gentamicin, if necessary, requires close medical supervision. For the treatment of infections of the genitourinary system, respiratory tract or abdominal cavity, gentamicin can be prescribed in doses appropriate to the individual patient. Higher doses may be necessary when treating tuberculosis or serious infections such as diseases of the circulatory system. However, the exact dose depends on the individual clinical condition and sensitivity of the patient.