Hyperthyroidism Experimental

Hyperthyroidism (experimental hyperthyreosis) is a form of thyroiditis caused by elevated levels of thyroid hormones. This is a fairly rare disease, but it can lead to serious health consequences. In this article, we will consider experimental hyperthyroidism as a rarer case of hyperthyroidism than hyperthyroidism associated with inflammation of the thyroid gland (also known as goiter) and hyperthyroidism caused by the formation of antibodies to thyroid tissue.

Experimental hyperthyroidism - rare

Hyperthyroidism is a disease manifested by excessive secretion of thyroid hormones, in which both the total mass of the organ increases and destructive tissue changes are noted. Chronic hyperthyroidism can be progressive. There is hyperplasia of follicle cells, i.e. division proceeds faster than the formation of colloid, and the gland is sharply increased in volume (up to 60 cm³ in adults). The composition of the gland is adipose – fat predominates over colloid. The function of the gland is increased - a lot of thyroxine is produced, but it is poorly absorbed by the tissues. The synthesis of proteins and plasma proteins may be affected, resulting in hypoproteinemia. Reduced tissue sensitivity to thyroid hormones. This is due to the accelerated movement of colloids in the vacuoles - their movements are sharp. The gland trembles strongly upon palpation. The parathyroid glands are often hypertrophied. The development of hyperthyroidism may be associated with the toxic effect of iodine, sometimes inaccurately determined in the primary form by the characteristic Zollinger-Ellison picture (atrophy of parafollicular cells, inflammation of the follicles). Thyroid dysfunction is very common after childbirth or in other acute toxic conditions. Premenopausal women often develop thyrotoxicosis due to low estrogen levels. The hyperthyroid phase of the manifest course is extremely rare; often patients themselves understand their condition, try to adhere to a diet, limit food and liquid intake (thin women imagine themselves as suffering from malnutrition). Tolerance to