Hyposplenia

Hyposplenia: A rare condition of the spleen

Hyposplenia, also known as hyposplenism, is a rare medical condition characterized by a reduced size or poor function of the spleen. The spleen is an important organ in our body that performs many important functions, including filtering blood, participating in the immune system, and participating in the process of blood formation.

With hyposplenia, the size of the spleen is significantly reduced and it may be significantly less functional. Typically, hyposplenia occurs due to congenital abnormalities or genetic disorders that lead to inadequate development of the spleen. In rare cases, hyposplenia may be an acquired condition caused by injury, infection, or other factors that damage the spleen.

One of the main consequences of hyposplenia is a decrease in the body's immune function. The spleen plays an important role in removing old or damaged blood cells and fighting infections. Hyposplenia increases the risk of developing serious infections, especially those caused by certain types of bacteria that are usually easily eliminated by a body with a normally functioning spleen.

In addition, hyposplenia can lead to blood abnormalities such as thrombocytopenia (low platelet count) or erythrocytopenia (low red blood cell count). This may lead to an increased tendency to bleed or become anemic.

The diagnosis of hyposplenia can be made using a variety of methods, including ultrasound of the spleen, computed tomography (CT), or magnetic resonance imaging (MRI). Treatment of hyposplenia is usually aimed at eliminating symptoms and compensating for the lack of spleen function. This may include taking antimicrobial medications to prevent infections, regular check-ups and consultations with your doctor to monitor the condition, and getting vaccinated against certain infections.

In conclusion, hyposplenia is a rare condition characterized by poor splenic function. This condition can affect the immune system and blood function. The diagnosis and treatment of hyposplenia requires the attention of medical professionals, and regular monitoring is necessary to maintain the patient's health and prevent complications.



Hyposplenia is an abnormal decrease in splenic function, manifested by poor blood circulation through the splenic veins, depletion of leukocytes and platelets in the bloodstream, and the appearance of Howell John-Wilson bodies. Hypersplenectomy - surgical removal of the spleen is accompanied by both hemostasis disorders and the body’s immunological reactivity. A significant deterioration in the hemostatic properties of blood (impaired platelet functionality) develops only after partial resection of the spleen. According to a number of other indicators, the state of the body after a total splenectomy returns to normal faster than after a partial splenectomy, especially if it is supplemented with intensive conservative therapy. The resistance of the hemostasis system to the development of hypocoagulation also causes an increase in sensitivity to a lack of blood supply to tissues, which aggravates the course of tissue hypoxia, delays the development of granulation tissue and is often accompanied by the development of staphyloma. All this requires the use of hemorestorative and cytoprotective therapy. It is carried out in accordance with the location and size of the parenchymal defect, the presence or absence of post-splenectomy portal fibrosis and its stage, the nature of the surgical intervention, the clinical course of infectious and inflammatory complications, concomitant diseases, indicators of the blood coagulation system and other laboratory indicators.

Treatment hyposp