Hemosiderin histiocytoma

Histocytic sideroblastic tumors account for approximately ~5% of all primary malignant tumors of internal organs. Histioctal sideroblastic tumor, characterized by a significant cellular component, in addition to stromal tissue and infiltrative cells, contains a large number of degenerating and dividing cells with a macrophage or histiocytic nucleus, as well as aggregates of erythrocytes.

The tumor process is characterized by a long evolution: 7-8 years from the onset of the first symptoms and the appearance of foci of destruction to the stage of tumor calcification, which is a rare diagnostic sign of siderine invasive histocytomatosis of the chest and vertebrae. Without calcification, tumor formations of this group cannot be completely classified as osteolytic. Calcification occurs at extremely late stages of the disease, since very long-term skeletal resorption is required, extending to sufficient volumes of bone tissue as



Histiocytes are macrophage cells that perform the functions of absorbing and recycling various pathological materials and substances. The detection of histiocytes in tissues and organs may indicate various pathological processes, for example, the presence of cancer, as well as other diseases. Some of the most common types of histiocyte are hy