Glidanil

Glidanil: description, application and possible side effects

Glidanil is an antidiabetic drug belonging to the group of sulfonylurea derivatives. This drug is used to treat type 2 diabetes mellitus, when compensation for hyperglycemia with diet, weight loss and physical activity is not possible. Glidanil is produced in Argentina by Kimica Montpellier and Bago Group Company.

The active ingredient of the drug is Glibenclamide. This is a synthetic substance that stimulates the release of insulin from the pancreas, which helps lower blood sugar levels. Glidanil is available in the form of 5 mg tablets.

When using Glidanil, some contraindications may occur. These include hypersensitivity to sulfonamide drugs, thiazade diuretics, diabetic precomatose and comatose state, ketoacidosis, extensive burns, surgery and trauma, intestinal obstruction, gastric paresis, conditions accompanied by impaired absorption of food, the development of hypoglycemia (infectious diseases, etc.) , hypo- or hyperthyroidism, impaired liver and kidney function, leukopenia, type 1 diabetes mellitus, pregnancy and lactation.

Side effects may also occur when using Glidanil. These may be disorders of the cardiovascular system and blood (thrombocytopenia, granulocytopenia, erythrocytopenia, pancytopenia, eosinophilia, leukocytopenia, agranulocytosis), nervous system and sensory organs (headache, dizziness, changes in taste), metabolic disorders (hypoglycemia, proteinuria, porphyria cutanea tarda), gastrointestinal disorders (liver dysfunction, cholestasis, dyspepsia) and allergic reactions (skin rashes).

Glidanil may interact with many other drugs, including systemic antifungals (azole derivatives), fluoroquinolones, tetracyclines, chloramphenicol (inhibits metabolism), H2-blockers, beta-blockers, ACE inhibitors, NSAIDs, MAO inhibitors, clofibrate, bezafibrate, probenecid , paracetamol, ethionamide, anabolic steroids, saluretics, diphenhydramine, quinidine, phenylbutazone, phenytoin, sulfonamide antibiotics, etc.

Before starting to use Glidanil, you should consult your doctor and inform him about all medications you are taking and your health condition. The dosage and duration of treatment should be prescribed by the doctor individually for each patient.

In general, Glidanil is an effective drug for the treatment of type 2 diabetes, but its use may be accompanied by some side effects and contraindications, so you must follow all your doctor’s recommendations.