Glycogenolysis

Glycogenolysis is an important biochemical process that occurs in humans and animals. It involves the breakdown of glycogen into glucose, which is used to produce energy. Glycogenolysis occurs mainly in the liver and muscles.

Glycogen is a polysaccharide that is a reserve source of energy for the body. Glycogen is stored in the liver and muscles in the form of granules, which consist of glucose molecules linked together by alpha-1,4-glycosidic bonds with branches formed by alpha-1,6-glycosidic bonds.

During glycogenolysis, glycogen is broken down into glucose. This process begins with glycogen phosphorylase, an enzyme that catalyzes the breaking of alpha-1,4-glycosidic bonds between glucose molecules in glycogen. The result of this process is the formation of glucose-1-phosphate molecules, which are further converted into glucose with the participation of other enzymes.

Glucose produced by glycogenolysis can be used for energy production or for glycogen synthesis in the body. In muscles, glucose is used to produce energy during exercise, and in the liver it can be released into the blood to maintain blood glucose levels.

Glycogenolysis is an important process for maintaining energy balance in the body. Disturbances in this process can lead to various diseases, such as glycogenosis, which are associated with impaired synthesis or breakdown of glycogen. Glycogenolysis is also an important process for athletes, who can use it to increase endurance and strength during training.

In conclusion, glycogenolysis is an important biochemical process that occurs in humans and animals. It allows you to use glycogen as a reserve source of energy and maintain energy balance in the body.



Glycogenolysis is a biochemical reaction in the body that occurs primarily in liver and muscle cells. It occurs to convert glycogen into glucose, the main source of energy for the body.

Glycogen is a reserve substance that accumulates in the cells of the liver, muscles and other tissues. It consists of long chains of glucose molecules linked together. During glycogenolysis, these chains are broken down into individual glucose molecules, which can then be used for energy.

The main enzyme involved in glycogenolysis is glycogen phosphorylase. When it is activated, glycogen begins to break down into glucose. This process occurs mainly in the liver and skeletal muscles, where glycogen accumulates.

Besides muscle and liver, glycogenolysis also occurs in several other tissues such as the kidneys, pancreas and heart. However, glycogenolysis plays a less important role in these tissues than in the liver and muscles.

Thus, glycogenolysis is an important process in the body that provides rapid access to glucose for energy in critical situations such as exercise or stress.



Glycogenogenesis is the physiological process of glycogen formation from simple sugars in liver cells, where glycogen accumulates and is used as an energy reserve. The sugary nature of the glycolytic process also contributes to its definition as a specific method of biotransformation of carbohydrates into energy. Unlike glycogenolysis, glycogen biosynthesis is not directly related to the formation of sugars. Glucose in the process of glycogenosis is formed only as the final product of the breakdown of polysaccharide granules accumulating in the liver during the destruction of the residues of synthesized adenosine diphosphate, resulting in the formation of free phosphodiopentaerythritol, which is the basis for the further generation of the polyribose II-phosphate chain. The disadvantage of glycogenogenesis is its “autonomy” from the processes of oxidation of substances, which is a negative factor in the implementation of regulatory mechanisms. All these features of glycogen metabolism create the main characteristic of energy exchange in tissues, providing the body with glycogen energy.