Glipizide (Glipiyde)

Glipizide: mechanism of action, application and side effects

Glipizide is a drug that is widely used to lower blood sugar levels in patients with non-insulin-dependent diabetes mellitus. This drug belongs to the group of sulfonylureas, which improve the action of insulin in the body by reducing blood glucose levels.

Mechanism of action

Glipizide (Glipiyde) is a drug that is widely used to treat non-insulin-dependent diabetes mellitus. This drug belongs to the class of sulfonylureas, which helps lower blood sugar in patients suffering from hyperglyxemia.

Sulfonylureas are one of the main classes of drugs used to treat diabetes mellitus. They work by increasing insulin release and improving peripheral insulin sensitivity. Thus, glipizide helps lower blood glucose levels, relieving the symptoms of diabetes.

Glipizide is given orally and is usually taken once daily before meals. The dosage may vary depending on the individual case, but the usual starting dose is 2.5-5 mg per day. If necessary, the dose can be increased to 20 mg per day.

Like any medicine, glipizide may cause side effects. The most common side effects are hypoglycemia, nausea, vomiting and allergic skin reactions. If side effects occur, you should consult a doctor.

Glipizide is available under a variety of brand names, including Gilbenese and Minodiab. These drugs contain glipizide as the active ingredient and are used to treat diabetes.

In conclusion, glipizide is an effective drug for the treatment of non-insulin-dependent diabetes mellitus. Despite possible side effects, this drug helps control blood glucose levels and improve the quality of life of patients. If you suffer from diabetes, be sure to discuss the use of glipizide with your doctor.

Glipizides are intermediate-acting antihyperglycemic drugs, sulfonylurea derivatives. The hypoglycemic effect of glipizides is due to increased sensitivity of peripheral tissues to insulin and increased insulin release, suppression of liver gluconeogenesis and slowdown of carbohydrate absorption in the intestine. Compared to other sulfonylurea derivatives (SMN and their salts), glipizides have a less pronounced stimulating effect on insulin secretion from pancreatic beta cells. The maximum therapeutic effect develops by the end of the first hour of taking glipizide and lasts from 8 to 12 hours. To prevent postprandial hyperglycemia, the dose is selected depending on the level of glucose in the blood before meals. For liver diseases, the doses of drugs are selected individually by the doctor. The drug glipizide is used for type 2 diabetes mellitus, both alone and in combination with metformin. High doses of glipizide are used to treat insulin resistance. Combined use