Glomerulonephritis Nephrotic

Nephrotic glomerulonephritis: understanding and treatment

Nephrotic glomerulonephritis, also known as chronic glomerulonephritis with nephrotic syndrome, is a serious kidney disease that can significantly affect a patient's health and well-being. In this article, we will review the basic aspects of nephrotic glomerulonephritis, including its definition, causes, symptoms and treatments.

Nephrotic glomerulonephritis is a form of glomerulonephritis in which the glomeruli of the kidneys become damaged, causing protein and other substances to leak into the urine. Patients with this disease often experience nephrotic syndrome, which is characterized by the following symptoms:

1. Proteinuria: The kidneys are unable to retain proteins and they are excreted into the urine. This may cause foamy urine or swelling around the eyes, legs, and other parts of the body.

2. Hypoalbuminemia: Due to the loss of protein in the urine, the level of albumin in the blood decreases in patients with nephrotic glomerulonephritis. This can cause swelling and affect the patient's condition.

3. Hyperlipidemia: Levels of lipids (fats) in the blood increase, which can lead to plaque formation in blood vessels and increase the risk of cardiovascular disease.

The causes of nephrotic glomerulonephritis can be varied. This may be the result of inflammation, immune disorders or genetic predispositions. Some common causes include immune glomerulonephritis, systemic diseases such as lupus or diabetes mellitus, and certain medications.

The diagnosis of nephrotic glomerulonephritis involves extensive testing of the patient's urine and blood, as well as a kidney biopsy to obtain a tissue sample for further analysis.

Treatment of nephrotic glomerulonephritis is aimed at controlling symptoms and slowing the progression of the disease. Includes the following approaches:

1. Drug therapy: Prescribing drugs such as corticosteroids and immunosuppressants to reduce inflammation and suppress the immune system.

2. Blood pressure control: Patients with nephrotic glomerulonephritis may need to control their blood pressure with medications and lifestyle changes.

3. Diet: It is recommended to follow a diet that limits salt and protein intake to reduce the burden on the kidneys.

4. Managing edema: Patients may be prescribed diuretics to eliminate edema and excess fluid from the body.

5. Control lipid levels: Regular monitoring and treatment of hyperlipidemia can help reduce the risk of cardiovascular complications.

6. Kidney Transplantation: In case kidney function is significantly reduced, kidney transplantation may be considered as a treatment option.

Nephrotic glomerulonephritis is a chronic disease that requires long-term and regular medical supervision. Patients should follow the doctor's recommendations, take prescribed medications and lead a healthy lifestyle.

In conclusion, nephrotic glomerulonephritis is a serious kidney disease characterized by protein leakage and various symptoms. It is important to consult a doctor in a timely manner for diagnosis and appropriate treatment. By following your doctor's recommendations and making lifestyle changes, patients with nephrotic glomerulonephritis can manage their condition and improve their quality of life.

Glomerulonephritis is a group of immune proliferative kidney diseases in which the primary morphological element of the lesion is changes in the glomeruli such as glomerulosclerosis and hyalinosis, combined with changes in the tubules such as interstitial fibrosis.