Glycogenesis

Glycogenesis: process of formation of glycogen

Glycogenesis is an important biochemical process during which the body synthesizes and stores glycogen. Glycogen is a polymer compound consisting of many glucose molecules and is the main storage source of energy in the body.

The process of glycogenesis occurs primarily in the liver and muscles. In the liver, glycogenesis serves to regulate blood glucose levels. When blood glucose levels rise (for example, after eating), the liver actively converts excess glucose into glycogen and stores it inside cells. This allows you to maintain stable blood glucose levels and provide the body with energy during periods of fasting or physical activity.

In muscles, glycogen serves primarily as an energy source for muscle contractions. During physical activity, muscles break down glycogen back into glucose and use it in the process of glycolysis to produce ATP (adenosine triphosphate), the main carrier of energy in cells. Thus, glycogenesis provides muscles with energy to perform physical activity.

The process of glycogenesis is controlled by a number of enzymes and regulatory proteins. The most important enzyme is glycogen synthase, which catalyzes the formation of glycogen from glucose molecules. The enzyme glycogen phosphorylase, on the contrary, breaks down glycogen, converting it back into glucose. Regulation of these enzymes allows the body to precisely control the formation and breakdown of glycogen, adjusting it to current metabolic needs.

Disturbances in the process of glycogenesis can lead to various pathological conditions. For example, genetic mutations affecting the activity of glycogenesis enzymes can lead to hereditary diseases such as glycogenosis. Glycogenosis is characterized by impaired formation or breakdown of glycogen and can present with a variety of symptoms, such as hypoglycemia (low blood glucose levels), muscle weakness and organomegaly (enlarged organs).

Overall, glycogenesis is an important process that provides energy to the body and regulates blood glucose levels. Understanding the mechanisms of glycogenesis is of great importance for the study of metabolic processes and the search for new approaches to the treatment of pathologies associated with it. Further research in this area will help expand our knowledge of the regulation of energy metabolism in the body and develop innovative treatments for glycogenesis-related diseases.

**Glycogenesis** is the process of glycogen synthesis that occurs in the liver, muscles and other tissues of the body. This process is necessary to maintain normal blood glucose levels.

Glycogen is a complex carbohydrate made up of many glucose molecules. It is stored in cells in the form of granules and is used as