Wegener S Granulomatosis

Wegener's Granulomatosis

Wegener's granulomatosis is a particularly malignant form of periarteritis nodosa. This is an autoimmune disease that most often affects the nasal passages, lungs and kidneys. At the same time, in addition to arthritis, characteristic granulomas form in these areas, purulent-necrotizing rhinitis, sinusitis, chronic otitis media, bronchitis, and septic fever (rarely) develop.

Without the necessary treatment, the disease will



Wegener's Granulomatosis: features of the disease and treatment methods

Wegener's granulomatosis, also known as Wegener's Granulomatosis, is a rare autoimmune disease that is characterized by damage to the blood vessels, nasal passages, lungs and kidneys, and the formation of characteristic granulomas. The disease can lead to serious complications, including septic fever and even death, if timely and effective treatment is not initiated.

The causes of Wegener's granulomatosis are not fully understood, but it is known that it is an autoimmune disease associated with the inability of the body's immune system to correctly identify its own tissues and cells. As a result, immune cells begin to attack blood vessels and other tissues, causing inflammation and the formation of granulomas.

The most common symptoms of Wegener's granulomatosis are chronic rhinitis, sinusitis, otitis media, bronchitis, as well as general fatigue, weight loss and fever. With a long course of the disease, serious complications can develop, such as glomerulonephritis, heart failure, pulmonary hemorrhage, aneurysms and even sepsis.

Various methods are used to diagnose Wegener's granulomatosis, including blood and urine tests, x-rays, computed tomography (CT), magnetic resonance imaging (MRI), and tissue biopsy.

Wegener's granulomatosis is treated using a combination of steroids and immunosuppressants such as cyclophosphamide and azathioprine. This therapy helps reduce inflammation and prevent further development of granulomas. In some cases, if there are severe complications, surgery may be required.

Although Wegener's granulomatosis is a serious disease, timely diagnosis and initiation of effective treatment can significantly improve the patient's prognosis and quality of life. It is important to seek medical help if you suspect this condition.



Wegrander's granuloma is a particularly malignant disease of the vascular system, which manifests itself in the form of pus and ulcers on various organs. The disease is associated with a disorder of the immune system and leads to serious damage to the blood vessels and lungs.

In people with granuloma vegranis, inflammation of the blood vessels can lead to the loss of the ability to function effectively. This in turn can cause various symptoms such as cough, coughing up blood, weight loss, increased heart rate and fatigue. If left untreated, the disease can be fatal.

Symptoms of the disease can appear in any part of the body and include signs such as: - Stubborn sores, spots or even scars. - Pain around large joints such as knees.

The most common manifestation of this disease is inflammation of the walls of blood vessels, which over time can cause them to rupture, release blood and become infected. This can lead to blood clots and bleeding. In addition, the blood supply to internal organs may be impaired. The disease can also lead