Hepatic Cell Failure

Hepatocellular failure, or hepatocellular failure, is a pathological condition in which the normal functioning of hepatocytes - liver cells - is disrupted.

This leads to a decrease in the synthetic function of the liver and the development of liver failure. The main causes of hepatocellular failure are acute and chronic liver diseases, such as viral hepatitis, alcoholic liver disease, autoimmune hepatitis, and drug-induced liver damage.

Clinically, hepatocellular failure is manifested by jaundice, hypoalbuminemia, coagulopathy, and hepatic encephalopathy. For diagnosis, a biochemical blood test and imaging methods for examining the liver are used. Treatment is aimed at eliminating the causes of the disease and maintaining liver function. If severe liver failure develops, a liver transplant may be required.