Histadine

Histadine: use, contraindications and side effects

Histadine (terfenadine) is a histamine H1 receptor blocker and is used to treat a variety of allergic reactions. The drug is manufactured by Amun Pharmaceutical Industries Co. in Egypt, and is available in the form of 60 mg tablets. In this article we will review the main characteristics of histadine, including indications for use, contraindications, side effects and special instructions.

Indications for use
Histadine is used to treat seasonal allergic rhinitis, allergic conjunctivitis, chronic idiopathic urticaria, atopic eczema, contact dermatitis, rashes, itching caused by liver damage, angioedema, allergic reactions caused by drugs, food, insect bites, bronchial asthma and colds ( as part of complex therapy). Histadine can also be used to prevent allergic reactions to the administration of radiocontrast agents.

Contraindications
It is not recommended to take Histadine if you are hypersensitive to the drug, including hydroxyzine. The drug is also contraindicated during pregnancy, breastfeeding, and in children under 2 years of age (up to 6 years of age if kidney or liver function is impaired). In case of impaired renal and liver function, as well as in the elderly, histadine should be taken with caution.

Side effects
Like any medicine, histadine can cause side effects. These may include weakness, headache, dizziness, sleep disturbance, drowsiness, nervousness, depression, fainting, convulsions, paresthesia, blurred vision, palpitations, prolongation of the QT interval, ventricular tachyarrhythmia, torsades de pointes, extrasystole, ventricular fibrillation, cardiac arrest, hypotension, hematopoietic disorders, thrombocytopenia, dry oral mucosa, increased appetite, dyspeptic symptoms, nausea, vomiting, abdominal discomfort, change in stool frequency, cholestasis, jaundice, hepatitis, dry mucous membranes of the throat and nose, cough, sore throat, bronchospasm, nosebleeds, frequent urination, dysmenorrhea, rash, eczema, thinning hair, alopecia, gynecomastia, decreased libido, hyperprolactinemia, erectile dysfunction, breast hypertrophy in men, angioedema, allergic reactions, including anaphylaxis.

special instructions
Histadine should be taken strictly as prescribed by your doctor, following the dosage and regimen recommendations. It is not recommended to exceed the recommended doses and duration of use. If side effects occur or your health condition worsens, you should immediately consult a doctor. Histadine may interact with some medications, so you should consult your doctor before taking it.

In conclusion, histadine is an effective drug for the treatment of various allergic reactions, but its use should be limited to indications and compliance with dosage and dosage recommendations. If side effects occur, you should consult a doctor to adjust your therapy.