Holocrine

Holocrine

Holocrine is a term used to characterize a gland or type of secretion in which the glandular cells are completely destroyed and their protoplasm is included in the secretion.

With the holocrine type of secretion, gland cells accumulate synthesized substances in the cytoplasm, increase in size and degenerate. Then the cell membrane is destroyed, and all cellular debris is released out along with the accumulated secretion. This happens, for example, in the sebaceous glands of the skin. Sebaceous cells, accumulating lipids, increase in volume and then lyse, releasing fat onto the surface of the skin.

Thus, a distinctive feature of holocrine secretion is the death of secretory cells in the process of secreting secretion. This leads to the need for constant renewal of gland cells.



Holocrine is a term used to describe glands and types of secretion where the glandular cells are destroyed and their contents become part of the secretion. This process occurs, for example, in the sebaceous glands, which secrete fat.

Holocrine glands have a number of advantages over other types of secretion. First, they provide rapid and efficient secretion, which can be useful in situations where it is necessary to quickly respond to changes in the environment. Secondly, holocrine cells can quickly adapt to changes in environmental conditions, which allows them to quickly adapt to new conditions.

However, holocrine glands also have their drawbacks. They may be less effective in producing large amounts of secretion, since cell destruction may result in fewer secretory cells. Additionally, holocrine glands may be more susceptible to damage and infection because their cells are rapidly destroyed.

Overall, holocrine glands are an interesting and efficient way of producing secretions that can be useful in a variety of situations. However, they also have their disadvantages, which must be taken into account when choosing the type of secretion for specific tasks.



Holocrine glands (glandula holocrina), or holocrinin type of secretion

The term is used to describe a type of secretory gland that has a special type of secretory process. In this case, the intracellular elements of the so-called salt mass are completely destroyed and, together with the separated contents, have lost contact with the wall of the gland and the corresponding duct, so their tissue essence becomes indistinguishable. Hence the name of the term, translated into Russian, according to the existing terminological tradition, as “holocrine” (the influence of the Latin word “holus” - whole, complete). Indeed, from the cytoplasm of both types of glands - intracellular, or endo-, and tubular, associated with the exocell, respectively called ecto- and exocytoplasm - after the phase of its secretion, there remains unpecked material of the most varied chemical and biological composition, including metabolic products,