Diffuse Thyrotoxic Goiter, Exophthalmic Goitre, Exophthalmic Goitre, Graves S Disease

Diffuse Thyrotoxic Goiter, Exophthalmic Goiter, Exophthalmic Goitre, Graves' Disease

Diffuse Thyrotoxic Goiter, Exophthalmic Goitre, Exophthalmic Goitre, Graves' Disease are a group of diseases united by a common pathogenesis and clinical manifestations. They are characterized by diffuse enlargement of the thyroid gland (goiter), increased function of the thyroid gland (thyrotoxicosis) and exophthalmos (protrusion of the eyeballs).

The cause of these diseases is increased production of autoantibodies to thyroid-stimulating hormone receptors. These autoantibodies stimulate the thyroid gland, which leads to its enlargement and increased function with the development of thyrotoxicosis.

Main clinical manifestations:

  1. Diffuse enlargement of the thyroid gland (goiter)
  2. Tachycardia, tremor, sweating and other symptoms of thyrotoxicosis
  3. Exophthalmos (protrusion of the eyeballs)
  4. Mostly in young and middle-aged women

Diagnosis is based on the clinical picture, ultrasound data of the thyroid gland, determination of thyroid hormones and autoantibodies.

Treatment includes thyrostatic drugs, radioiodine therapy, and in some cases, surgery. The prognosis with adequate treatment is usually favorable.



Diffuse thyrotoxic-diffuse goiter is a pathological condition in which the functioning of the thyroid gland is disrupted, usually caused by autoimmune thyroiditis occurring in it. With this disease, diffuse inflammatory processes develop in the thyroid gland, which leads to changes in the structure of its tissue. The main signs of this disease are an increase in organ volume and excessive production of hormones. The presence of diffuse changes in this gland is fraught with the development of thyrotoxicosis.

Exophthalmic-basal goiter (Graves' disease, or diffuse ophthalmopathy) is a rather rare, but very dangerous chronic disease of the thyroid gland, which occurs in the form of its gradual destruction. The duration of this process, as a rule, is tens of years or even centuries. The disease is characterized by various external manifestations affecting the neck, eyes and face. The most important sign of this pathology is the bulging of the eyeballs with dilation of their pupils and pronounced swelling of the tissue. Very often, already in the first place diagnosing problems with protrusion of the eyes, it is also observed