Keratinization (Comification)

Keratinization is the process of cells turning into keratinized cells containing the protein keratin. Keratinization is also called keratinization.

Keratinization occurs in the upper layers of the skin, where cells in the epidermis (the top layer of skin) gradually die and are replaced by keratinized cells. These dead skin cells form the stratum corneum, which protects the underlying layers of skin from external influences.

The process of keratinization begins in the lower layers of the epidermis, where basal cells begin to produce keratin. As cells move to the surface of the skin, their nuclei are destroyed and the cytoplasm is filled with keratin fibrils. Eventually, completely keratinized squamous cells are sloughed off from the surface of the skin.

Keratification is an important process that ensures the protective function of the skin. Disturbances in keratinization can lead to various skin diseases.

Keratification or Comification is the process of changing the skin on the surface of the body into a keratinized layer of cells. This process usually occurs in older people and is associated with age-related changes in the skin and the body as a whole.

Keratinization is not an infectious disease, but may be associated with skin aging, circulatory disorders, hormonal