Insulocyte Basophil

Basophilic insulinocytes (i. Basophilus, LNH; cellula Beta; synonym: beta-cellula, b-cellula) are pancreatic cells that produce the hormone insulin. They are one of the main cells that regulate blood glucose levels.

Basophil insulin cells are round in shape and are found in the islets of Langerhans, which are located in the pancreas. These cells are large and contain many granules containing insulin. Insulin is a hormone that regulates blood glucose levels, helping the body use glucose as an energy source.

When blood glucose levels rise, basophilic insulin cells begin to produce insulin, which helps glucose enter the cells and be used in the metabolic process. When blood glucose levels drop, insulin cells stop producing insulin, allowing glucose to freely leave the cells.

An important factor influencing the functioning of basophilic insulocytes is blood sugar level. If sugar levels rise, insulin cells begin to produce more insulin in order to lower blood glucose levels and prevent the development of diabetes. If the sugar level decreases, the insulin cells stop producing insulin and allow glucose to leave the cells, preventing the development of hypoglycemia.

In addition, basophilic insulinocytes are also involved in other processes related to glucose metabolism. For example, they may be involved in regulating hormones such as glucagon and somatostatin, which also affect blood glucose levels.

Basophilic insulinocytes - (syn. beta cells) - processes of neurons in the ganglion cells of the medulla of the end plate, secreting mainly i. The first case of detection of basophilic insulocyte in the pancreas made the function of this new type of cellular elements unclear, despite the fact that its further study in connection with the study of pancreatic diseases showed its participation in endocrine processes. Insulocytes differ basophilically from all previously known types of endocrine cells by the presence on their surface of various sizes of modified goblet cells (basophilia), the length of which ranges from 7 to 25 μm, and the width from 0.3 to 0.5 μm, the number of which reaches to such an extent that they create a kind of “pinnate” cytoplasm (hence the term “basophilic”).