Itramicol

Itramicol: description, application, side effects and other features

Itramycol (international name itraconazole) is an antifungal drug derived from imidazole and triazole. It is used to treat various types of mycoses, including onychomycosis, mycoses of the skin, oral cavity and eyes caused by dermatophytes, yeasts and molds, systemic tropical mycoses, vulvovaginal candidiasis.

Itramikol is produced by the company Moskhimfarmpreparaty named after. ON THE. Semashko is in the form of capsules of 100 mg containing the active substance - itraconazole. The drug is not recommended for use in case of hypersensitivity, pregnancy and lactation.

Like any medicine, Itramicol may cause side effects. Among them are dyspepsia, abdominal pain, constipation, hepatitis, increased appetite, headache, dizziness, peripheral neuropathies, dysmenorrhea, increased levels of transaminases in the blood plasma, itching, thrombocytopenia, leukopenia, prolongation of bleeding time, edema, hypokalemia, weight gain, hyperammonemia, alopecia, angioedema, urticaria, itching.

Itramicol may also interact with other medications. For example, it is incompatible with terfenadine, astemizole, lovastatin, oral forms of midazolam and triazolam. It also enhances and/or prolongs the effect of oral anticoagulants, cyclosporine A, digoxin, methylprednisolone, warfarin, vincristine, calcium channel blockers. Rifampicin and phenytoin reduce the bioavailability of itraconazole, antacids - absorption (the interval separating their administration should be at least 2 hours).

When using Itramicol, special conditions must be taken into account. In patients with liver cirrhosis and/or renal impairment, plasma concentrations of itraconazole should be monitored and the dose adjusted if necessary. Women of childbearing age should always use contraception during treatment.

In conclusion, Itramicol is an effective antifungal drug that can be used to treat various types of mycoses. Like any drug, it has its side effects and requires special attention when used in combination with other drugs. Therefore, before using Itramicol, you should consult your doctor and strictly follow the recommendations on dosage and duration of treatment.