Calcinosis

Calcinosis (calcification) is a pathological process in various organs and tissues, characterized by the formation of excess calcium salts (mainly calcium phosphate) and accompanied by the deposition of lime in organs and tissues in the form of microliths and larger stones. Calcification can result from either a normal physiological process or a pathological condition.

Calcifications can occur as a result of various pathological processes and conditions, such as:

  1. Osteoarthritis is a disease in which articular cartilage breaks down, leading to the formation of calcium deposits.
  2. Atherosclerosis is a process that leads to the deposition of cholesterol plaques containing calcium on the walls of blood vessels.
  3. Soft tissue calcification is the formation of excess calcium in muscles, ligaments, tendons, fascia and other tissues.
  4. Calcification in the lungs is a pathological condition that is accompanied by the deposition of calcium in the lung tissue.
  5. Renal calcification is excessive deposition of calcium in the kidney tissue, which can lead to impaired kidney function.

One of the most common types of calcification is coronary artery calcification, which can lead to the development of cardiovascular diseases such as myocardial infarction and heart failure.

Overall, calcinosis is a serious condition that can lead to serious complications and even death. Therefore, it is very important to diagnose and treat this disease in a timely manner.



Calcification is the name given to excessive deposition of calcium salts in tissues, mainly in connective tissues. The most common areas affected by calcification are cartilage, soft tissues, organs, joints, blood vessels, and muscles. Any organ in the body can become calcified, although the musculoskeletal system is most often affected. Calcium deposition in tissue structures can be either minor or cause serious deformation of the organ. This leads to dysfunction and diseases of organs of various localizations, which negatively affects the quality of life of patients.

Calcific metastases in the lung tissue can spread from other organs. This phenomenon is associated with the activation of collagenase, which destroys paren cells