Calcification of Blood Vessels, Generalized

Generalized calcification of blood vessels (calcinosis vasorum sanguineorum generalisata) is a rare systemic disease characterized by the deposition of calcium salts in the walls of blood vessels.

Causes

The exact causes of the development of generalized vascular calcification are unknown. It is assumed that the underlying causes are disturbances in the metabolism of calcium and phosphorus. The disease can be primary or develop against the background of chronic renal failure, hyperparathyroidism, hypervitaminosis D and some other conditions.

Symptoms

The main clinical manifestations are associated with vascular damage and tissue ischemia. The skin, subcutaneous tissue, and muscles are most often affected. There is pain, decreased sensitivity, and trophic disturbances in the affected areas. The development of ulcers and necrosis is possible. When internal organs are involved, corresponding disturbances in their function are observed.

Diagnostics

The diagnosis is established on the basis of the clinical picture, laboratory and instrumental studies. Radiography is important, in which multiple linear shadows of calcium are determined in the projection of the vessels.

Treatment

Treatment is aimed at correcting the metabolic disorders underlying the disease. Symptomatic therapy and surgical treatment of ulcers and necrosis are carried out. The prognosis depends on the severity and extent of the process. With timely diagnosis and adequate treatment, it is possible to slow the progression of the disease.

Calcification of blood vessels is the process of proliferation and deposition of calcium salts in the walls of arterial vessels due to metabolic and circulatory disorders.

Vascular calcification can develop in various pathological processes, including hyperparathyroidism, aneurysms, atherosclerosis, myocardial hypertrophy and other diseases. At the same time, calcium