Caldopa

Kaldopa: Antiparkinsonian drug from India

Kaldopa, also known by its international name Levodopa, is a pharmaceutical drug manufactured in India by Kadila Pharmaceuticals. It belongs to the group of antiparkinsonian dopaminergic drugs and is widely used to treat Parkinson's disease and symptomatic parkinsonism.

Kaldopa is available in the form of tablets containing 250 mg or 500 mg of the active ingredient, Levodopa. This substance is a key component of the drug and has an antiparkinsonian effect.

The drug is used to relieve symptoms of Parkinson's disease, such as tremors, muscle stiffness, and poor coordination. It may also be used for symptomatic parkinsonism due to other causes.

Kaldopa has some contraindications and restrictions for use. For example, it is not recommended for severe atherosclerosis, hypertension, liver, kidney, blood diseases, glaucoma, melanoma, bronchial asthma, mental illness and uncompensated pathology of the cardiovascular, respiratory and endocrine systems. The use of Kaldopa is also limited during pregnancy, breastfeeding, children under 12 years of age, and in patients with a history of myocardial infarction.

Like any medicine, Kaldopa may cause side effects. Some of them include choreoathetoid hyperkinesis, arrhythmia, psychotic and paranoid reactions, dyspeptic symptoms, gastrointestinal ulceration, headache, dizziness, visual disturbances, hemolytic anemia, agranulocytosis and leukopenia, alopecia and allergic reactions.

It is important to note that Kaldopa may interact with some other drugs. For example, it weakens the effect of vitamin B6 and enhances the effect of monoamine oxidase inhibitors (MAOIs).

Data on overdose with Kaldopa are limited, and there are no special instructions for the use of this drug.

In conclusion, Kaldopa is an antiparkinsonian drug manufactured in India. It contains the active ingredient Levodopa and is used to treat Parkinson's disease and symptomatic parkinsonism. Like any other drug, Kaldopa has its own contraindications, side effects and interactions with other drugs. Before using Kaldopa, it is important to consult your doctor and follow his recommendations.

Literature:
Encyclopedia of Medicines, 2004