Cardiostatin

Cardiostatin: HMG-CoA reductase inhibitor for the treatment of hypercholesterolemia and atherosclerosis

Cardiostatin (Lovastatin) is a lipid-lowering drug that belongs to the class of HMG-CoA reductase inhibitors. The drug is used to treat hypercholesterolemia and atherosclerosis.

Cardiostatin is produced by Makis-Pharma in Russia and is available in the form of tablets with dosages of 20 mg and 40 mg. The active substance is lovastatin.

Indications for the use of Cardiostatin include hypercholesterolemia (primary with a high content of LDL types IIa and IIb) in the absence of effect from diet therapy, combined with hypertriglyceridemia (hyperlipoproteinemia type IIb) and atherosclerosis.

Contraindications to the use of Cardiostatin include hypersensitivity, impaired renal function, severe liver failure, persistent increase in plasma transaminase levels, pregnancy, lactation and childhood.

Cardiostatin may cause side effects, including impaired liver function, increased transaminase levels, dizziness, mental disorders, convulsions, dyspepsia, flatulence, nausea, vomiting, heartburn, dry mouth, taste disturbance, anorexia, constipation/diarrhea, hepatitis, headaches, muscle pain, myopathies, rhabdomyolysis, general weakness, chest pain, arthralgia, insomnia, paresthesia, optic atrophy, cataract development and allergic reactions.

Cardiostatin may interact with certain drugs, including cyclosporine, cholestyramine, bile acids, fibrates, niocin, itraconazole and other azole antifungals, erythromycin, and cyclosporine. You should also be careful when using Cardiostatin simultaneously with immunosuppressants.

In case of an overdose of Cardiostatin, side effects may increase. Treatment is symptomatic.

In patients taking immunosuppressants or with severe renal dysfunction, the dose should not exceed 20 mg per day. During treatment, patients should be on a standard low-cholesterol diet. It is recommended to carefully monitor your general condition and periodically check your blood cholesterol levels and liver function.

In general, Cardiostatin is an effective treatment for hypercholesterolemia and atherosclerosis, but its use should only be under medical supervision and taking into account the individual characteristics of each patient. It is also necessary to follow the correct dosage regimen and monitor for possible side effects.