Carmustine (Carmustine, Bcnu)

Carmustine (Bcnu) is a drug (alkylated agent) used to treat certain types of malignant tumors, including lymphomas and brain tumors.

Carmustine belongs to the group of cytostatic drugs - alkylating agents. It acts by alkylation of cell DNA, which leads to disruption of its structure and function, inhibition of nucleic acid synthesis and cell death.

Carmustine is used to treat various malignant tumors:

1. Hodgkin's lymphomas and non-Hodgkin's lymphomas
2. Multiple myeloma
3. Brain tumors (gliomas, medulloblastomas)
4. Mammary cancer
5. Lung cancer

Carmustine is administered intravenously in the form of infusions. It has a pronounced toxic effect, especially on the bone marrow, so careful monitoring of blood tests is necessary during treatment. Other side effects include nausea, vomiting, and pneumonia. The drug has a cumulative effect, so its toxicity increases with increasing dose and duration of treatment.

Thus, carmustine is an important antitumor agent for the treatment of lymphomas, brain tumors and some other oncological diseases. However, its use is limited by severe toxicity, especially with long-term use.

Carmustine is a drug that is used to treat various types of malignancies, including lymphomas and brain tumors. This drug is an alkylating agent and belongs to the nitrosourea group.

Carmustine was developed in the 1970s and has since been widely used in medical practice. It works by damaging the DNA of cancer cells, causing them to die. The drug can also be used in combination with other drugs to enhance the effect.

However, Carmustine has its side effects such as nausea, vomiting, diarrhea, headache and blurred vision. Allergic reactions and bone marrow suppression are also possible, which can lead to the development of leukopenia, thrombocytopenia and anemia.

Before starting treatment with Carmustine, it is necessary to conduct a thorough examination of the patient and determine his individual sensitivity to the drug. Treatment should be carried out under the supervision of a physician, who will monitor the patient’s condition and adjust the dosage if necessary.

In general, Carmustine remains one of the most effective drugs for the treatment of malignant neoplasms. However, due to its side effects and possible complications, its use should be strictly controlled and carried out only under the supervision of qualified specialists.